Bioinformatics and Integrative Genomics (BIG) Facility
The Bioinformatics and Integrative Genomics Facility at ICAR-Indian Institute of Spices Research was established in 2000 as a sub-center under the BTIS network. It serves as a hub connecting multidisciplinary scientists, IT professionals, and technical experts, providing essential bioinformatics support and training to researchers and students. The facility plays a crucial role in assisting various divisions of the institute with computational expertise. Our team specializes in analyzing gene expression and regulation at transcriptional, post-transcriptional, and epigenetic levels. We also employ various 'omics' technologies to study the soil microbiome and its influence on plant health and disease resistance. Additionally, we develop and implement computational tools to analyze sequence data, addressing key research questions such as gene expression during plant-pathogen interactions, cellular responses to environmental changes, and the co-evolution of host and pathogen genomes. The facility also supports molecular docking, virtual screening, and structure-based drug discovery, aiding research on protein-ligand interactions, bioactive compounds, and plant-microbe interactions, contributing to functional genomics, phytochemical bioactivity, and crop improvement.
BIG Facility has organized the following workshops in the past:
